CRISPR/Cas9-induced disruption of wt1a and wt1b reveals their different roles in kidney and gonad development in Nile tilapia

Developmental biology

DongnengJiang¹ 

关键词: Amh;    Anti-Müllerian hormone;    Cyp19a1a;    cytochrome P450, family 19, subfamily A, polypeptide 1a;    Cyp11b2;    cytochrome P450, family 11, subfamily B, polypeptide 2;    dah;    days after hatching;    Dmrt1;    double sex- and mab-3-related transcription factor-1;    Gsdf;    gonadal soma-derived factor;    ISH;    in situ hybridization;    MD;    Müllerian duct;    PGC;    primordial germ cell;    Sf-1;    nuclear receptor subfamily 5, group a, member 1;    Vasa;    DEAD-box helicase 4;    WD;    Wolffian duct;    Wt1;    Wilms tumor 1;    Wilms tumor 1;    Nile tilapia;    CRISPR/Cas9;    Kidney;    Gonad;    Sex determination and differentiation;    Reproduction;   

DOI  :  10.1016/j.ydbio.2017.05.017

学科分类：生物科学（综合）

来源: Academic Press

【 授权许可】

CC BY