Application of chitosan as support for immobilization of enzymes of industrial interest

Quimica nova

Giordano, Raquel de L. C.¹  Mendes, Adriano A.²  Oliveira, Pedro C. de³  Castro, Heizir F. de³ 

[1] Universidade Federal de São Carlos, São Carlos, Brasil;Universidade Federal de São João Del-Rei, Sete Lagoas, Brasil;Universidade de São Paulo, Lorena, Brasil

关键词: chitosan;    immobilization;    enzymes.;   

DOI  :  10.1590/S0100-40422011000500019

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Chitosan, poly[β-(1-4)-linked-2-amino-2-deoxy-D-glucose],is the N-deacetylated product of chitin which is a major component of arthropodand crustacean shells such as lobsters, crabs, shrimps, and cuttlefishes. Inaddition, chitosan has many significant biological and chemical properties suchas biodegradability, biocompatibility and bioactivity as well as polycationicproperties. Thus, it has been widely used in many industrial and biomedicalapplications including wastewater treatment, chromatographic support, carriersfor controlled drug delivery and enzyme immobilization. This review is an insightinto the exploitation of utilization of chitosan based-supports in differentgeometrical configurations on the immobilization of enzymes by different protocolsfor further application in biotransformation reactions.

【 授权许可】

CC BY