Antigenic Variation in Plasmodium falciparum Malaria Involves a Highly Structured Switching Pattern

PLoS Pathogens

Sunetra Gupta¹  Andrew Serazin²  Caroline O. Buckee³  Chris I. Newbold³  Mario Recker³  Zóe Christodoulou⁴  Sue Kyes⁴  Robert Pinches⁴  Amy L. Springer⁴ 

[1] Department of Biology, Amherst College,Amherst, Massachusetts, United States of America;Department of Epidemiology, Harvard School ofPublic Health, Boston, Massachusetts, United States of America;Department of Zoology, University of Oxford,Oxford, United Kingdom;Weatherall Institute of Molecular Medicine,University of Oxford, John Radcliffe Hospital, Oxford, UnitedKingdom

关键词: Cloning;    Parasitic diseases;    DNA transcription;    Antigenic variation;    Immune response;    Gene expression;    Malarial parasites;    Plasmodium;   

DOI  :  10.1371/journal.ppat.1001306

学科分类：生物科学（综合）

来源: Public Library of Science

【 授权许可】

CC BY