State of the art of figures of merit in multivariate calibration

Quimica nova

Valderrama, Patrícia¹  Poppi, Ronei J.¹  Braga, Jez W. B.¹ 

[1] Universidade Estadual de Campinas, Campinas, Brasil

关键词: figures of merit;    multivariate calibration;    net analyte signal.;   

DOI  :  10.1590/S0100-40422009000500034

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

The validation of an analytical procedure must be certified through the determination of parameters known as figures of merit. For first order data, the acuracy, precision, robustness and bias is similar to the methods of univariate calibration. Linearity, sensitivity, signal to noise ratio, adjustment, selectivity and confidence intervals need different approaches, specific for multivariate data. Selectivity and signal to noise ratio are more critical and they only can be estimated by means of the calculation of the net analyte signal. In second order calibration, some differentes approaches are necessary due to data structure.

【 授权许可】

CC BY