期刊论文详细信息
Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society
n‐3 Polyunsaturated fatty acids and mast cell activation
关键词: EPA;    DHA;    Fcɛ;    RI;    lipid rafts;    eicosanoid;   
DOI  :  10.1189/jlb.2RU0814-388R
学科分类:生理学
来源: Federation of American Societies for Experimental Biology
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【 摘 要 】

Mastcellsareknowntoplayavitalroleinthedevelopmentofinflammationinallergicresponses.Recentstudieshaveindicatedthatmastcellactivationcouldbemodulatedbyn‐3PUFAs,whichhaveawiderangeofwell‐documentedhealthbenefits.Inourreview,wesummarizetherecentfindingsandpotentialmechanismsoftheeffectofn‐3PUFAsonmastcellactivation.Thisknowledgecouldprovidenewstrategiesforthedevelopmentoftherapeuticinterventionsfordiseasesmediatedbymastcells...

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