El envejecimiento oxidativo inflamatorio: una nueva teoría con implicaciones prácticas

MEDISUR

Leocadia Amores Hernández¹  Ángel Julio Romero Cabrera¹ 

[1] Hospital General Universitario Dr. Gustavo Aldereguía Lima. Cienfuegos

关键词: envejecimiento;    estrés oxidativo;    inflamación;    enfermedades crónicas;    longevidad;   

DOI  :  

学科分类：医学（综合）

来源: Centro Provincial de Informacion de Ciencias Medicas de Cinfuegos

【 摘 要 】

Oxidative stress causes an impairment of the physiological systems essential for maintaining homeostasis, including the immune system. Immunedysregulationleads to achronic low-grade inflammatory statein aging. This is the basis of the new integrative theory called oxy-inflamm-aging. The present article describes the foundations of this theory, the current research studies that support it, and its link with the pathogenesis of some age-related diseases. It is concluded that the adoption of a healthy lifestyle from an early age can contribute to a successful aging. The benefits of caloric restriction and antioxidant supplements are still under study in order to preventoxidative stressandinflammation , and consequently achieve greater longevity and reduce the burden of age-associated diseases.

【 授权许可】

CC BY