Treg cells: a potential regulator for IL-22 expression?

International Journal of Clinical and Experimental Pathology

Shuman Lin¹ 

关键词: Interleukin-22;    regulatory (Treg) cells;    T helper cells;    innate immune cells;   

DOI  :  

学科分类：生理学与病理学

来源: e-Century Publishing Corporation

【 摘 要 】

Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.

【 授权许可】

CC BY-NC