期刊论文详细信息
Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society
Dendritic cell science: more than 40 years of history
关键词: antigen‐;    presenting cells;    innate immune recognition;    adaptive immunity;    immunotherapy;   
DOI  :  10.1189/jlb.0512263
学科分类:生理学
来源: Federation of American Societies for Experimental Biology
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【 摘 要 】

Over40yearsofresearchintothefieldofDCshasrevolutionizedourunderstandingintotheactivationandregulationoftheimmunesystem.ThisminireviewdiscussesthemajorbreakthroughsinDCsciencethathavepavedthewaytothe2011NobelPrizeinPhysiology‐MedicineawardedtoBruceA.BeutlerandJulesA.Hoffmann(fortheirdiscoveriesininnateimmunerecognition)andRalphM.Steinman(forhisdiscoveryoftheDC)...

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