A follow-up study of first episode major depressive disorder. Impairment in inhibition and semantic fluency—potential predictors for relapse?

Frontiers in Psychology

Marit Schmid¹ 

关键词: first-episode major depression;    follow-up;    executive function;    inhibition;    semantic fluency;    relapse;   

DOI  :  10.3389/fpsyg.2013.00633

学科分类：心理学（综合）

来源: Frontiers

【 摘 要 】

The present study investigated the Executive Functions (EF) of inhibition, mental flexibility and phonemic and semantic fluency in a 1-year follow-up assessment of patients diagnosed with first episode Major Depressive Disorder (MDD). In the acute phase, the patient group performed significantly poorer compared to the control group (CG) in inhibition and semantic fluency. The present study pursued these findings from the acute phase to see if the impairment seen in inhibition and semantic fluency in the acute phase normalized or persisted in the follow-up assessment. In addition, the present study investigated the association between poor inhibition and semantic fluency performance and the experience of relapse during the 1-year period. Twenty eight patients and 28 individually matched control subjects were included. EF was reassessed using three tests from the Delis Kaplan Executive Function System (D-KEFS).

【 授权许可】

CC BY