Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: A Prospective Pilot Study

Frontiers in Medicine

Agnese Ozolina¹ 

关键词: acute respiratory distress syndrome;    lung injury;    plasminogen activator inhibitor-1;    tissue factor;    tissue plasminogen activator;    ventilator-associated lung injury;   

DOI  :  10.3389/fmed.2016.00064

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

IntroductionCoagulation and fibrinolysis remain sparsely addressed with regards to acute respiratory distress syndrome (ARDS). We hypothesized that ARDS development might be associated with changes in plasma coagulation and fibrinolysis. Our aim was to investigate the relationships between ARDS diagnosis and plasma concentrations of tissue factor (TF), tissue plasminogen activator (t-PA), and plasminogen activator inhibitor-1 (PAI-1) in mechanically ventilated patients at increased risk of developing ARDS.

【 授权许可】

CC BY