Antioxidant Effects of the Quercetin in the Jejunal Myenteric Innervation of Diabetic Rats

Frontiers in Medicine

Sara R. Garcia de Souza¹ 

关键词: diabetes mellitus;    enteric nervous system;    glia;    neuroprotection;    quercetin;   

DOI  :  10.3389/fmed.2017.00008

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

PurposeEnteric glial cells (EGCs) exert a critical role in the structural integrity, defense, and metabolic function of enteric neurons. Diabetes mellitus is a chronic disease characterized by metabolic disorders and chronic autonomic neuropathy. Quercetin supplementation, which is a potent antioxidant, has been used in order to reduce the effects of diabetes-induced oxidative stress. The purpose of this research was to investigate the effects of quercetin supplementation in the drinking water at a daily dose of 40 mg on the glial cells and neurons in the jejunum of diabetic rats.

【 授权许可】

CC BY