New insights into the anti-PD-L1 and anti-PD-1 reagents in cancer therapy:

European Journal of Inflammation

ChengChen¹ 

关键词: cancer;    immune evasion;    immunotherapy;    PD-L1;    PD-1;   

DOI  :  10.1177/1721727X15626423

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Immunotherapy that inhibits the interaction between programmed death ligand 1 (PD-L1), present on the surface of tumor or antigen-presenting cells, and programmed death 1 (PD-1), present on the surface of activated lymphocytes, is generating much excitement and enthusiasm. Although considerable knowledge has been accumulated on anti-PD-L1 and anti-PD-1 reagents, discovering immunotherapy-associated issues still remains a pressing task for the researchers and clinicians.

【 授权许可】

CC BY-NC