The evidence behind the use of platelet-rich plasma (PRP) in scar management: a literature review:

Scars, Burns & Healing

Osaid HAlser¹ 

关键词: Atrophic;    concentrate;    keloid;    management;    platelet;    platelet-rich plasma;    PRP;    scar;    traumatic;   

DOI  :  10.1177/2059513118808773

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Introduction:Autologous platelet-based concentrates represent increasingly popular adjuncts to a variety of medical, surgical and aesthetic interventions. Their beneficial potential rests on the ability to deliver a high concentration of growth factors to the target tissues. There are currently no reports in the literature appraising the evidence behind the use of platelet-rich plasma (PRP) in scar management.Methods:A detailed English literature review was conducted using PubMed Medline, Embase and Web of Science; the manuscripts were appraised and classified according to the Joanna Briggs Institute Levels of evidence. The results are presented in descending order of evidence separately for atrophic, keloid, surgical and traumatic scars.Discussion:On the basis of level 1 evidence currently available, it appears that PRP can improve the quality of atrophic acne scars treated with ablative fractional CO2 laser and decrease the duration of laser-related side effects including oedema and erythema. Regarding ...

【 授权许可】

CC BY