A Perspective on the Use of NB-UVB Phototherapy vs. PUVA Photochemotherapy

Frontiers in Medicine

Sally H. Ibbotson¹ 

关键词: UVB;    PUVA therapy;    phototherapy;    skin diseases;    psoriasis;    eczema;    vitiligo;   

DOI  :  10.3389/fmed.2018.00184

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

Narrowband UVB (NB-UVB) phototherapy and psoralen-UVA (PUVA) photochemotherapy are widely used phototherapeutic modalities for a range of skin diseases. The main indication for NB-UVB and PUVA therapies is psoriasis, and other key diagnoses include atopic eczema, vitiligo, cutaneous T-cell lymphoma (CTCL), and the photodermatoses. The decision on choice of phototherapy is important and NB-UVB is usually the primary choice. NB-UVB phototherapy is a safe and effective therapy which is usually considered when topical agents have failed. PUVA requires prior psoralen sensitization but remains a highly effective mainstay therapy, often used when NB-UVB fails, there is rapid relapse following NB-UVB or in specific indications, such as pustular or erythrodermic psoriasis. This review will provide a perspective on the main indications for use of NB-UVB and PUVA therapies and provide comparative information on these important dermatological treatments.

【 授权许可】

CC BY