The Future Liver Remnant in Patients Undergoing the Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy (ALPPS) Maintains the Immunological Components of a Healthy Organ

Frontiers in Medicine

Ram Venkatesh Anantha¹ 

关键词: liver metastases;    ALPPS;    hepatectomy;    liver regeneration;    flow cytometry;    immunophenotyping;   

DOI  :  10.3389/fmed.2016.00032

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

Background and AimsA short-interval, two-stage approach termed associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) increases the number of patients with extensive malignant disease of the liver and a small future liver remnant (FLR) that can undergo liver resection. While this approach results in accelerated liver hypertrophy of the FLR, it remains unknown whether this phenomenon is restricted to liver parenchymal cells. In the current study, we evaluated whether ALPPS alters the immunological composition of the deportalized lobe (DL) and the FLR.

【 授权许可】

CC BY