Strain-Specificity and Disease-Specificity of Probiotic Efficacy: A Systematic Review and Meta-Analysis

Frontiers in Medicine

Lynne V. McFarl¹ 

关键词: strain specificity;    disease specificity;    probiotic strains;    meta-analysis;    pooling data;    antibiotic-associated diarrhea;    Clostridium difficile;    Saccharomyces;    Lactobacillus;   

DOI  :  10.3389/fmed.2018.00124

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

BackgroundAs the use and diversity of probiotic products expands, the choice of an appropriate type of probiotic is challenging for both medical care professionals and the public alike. Two vital factors in choosing the appropriate probiotic are often ignored, namely, the probiotic strain-specificity and disease-specificity for efficacy. Reviews and meta-analyses often pool together different types of probiotics, resulting in misleading conclusions of efficacy.

【 授权许可】

CC BY