Frontiers in Pediatrics | |
Cardiopulmonary Exercise Test Methodology for Assessing Exertion Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | |
Staci Stevens1  | |
关键词: functional capacity; stress test; oxygen consumption; post exertional malaise; functional impairment; | |
DOI : 10.3389/fped.2018.00242 | |
学科分类:儿科学 | |
来源: Frontiers | |
【 摘 要 】
Background: Concise methodological directions for administration of serial cardiopulmonary exercise testing (CPET) are needed for testing of patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Maximal CPET is used to evaluate the coordinated metabolic, muscular, respiratory and cardiac contributions to energy production in patients with ME/CFS. In this patient population, CPET also elicits a robust post-exertional symptom flare (termed, post-exertional malaise); a cardinal symptom of the disease. CPET measures are highly reliable and reproducible in both healthy and diseased populations. However, evidence to date indicates that ME/CFS patients are uniquely unable to reproduce CPET measures during a second test, despite giving maximal effort during both tests, due to the effects of PEM on energy production.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201901224703094ZK.pdf | 427KB | download |