Effect of atypical antipsychotics on body weight in geriatric psychiatric inpatients:

SAGE Open Medicine

Eugene YHYeung¹ 

关键词: Antipsychotic;    body weight;    elderly;    aripiprazole;    olanzapine;    risperidone;   

DOI  :  10.1177/2050312117708711

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Background:Studies suggest that antipsychotic-induced weight gain is not a great concern in the elderly population. This study investigated the weight change in elderly patients with various treatment duration and antipsychotics. Part 1 of the study was to determine whether atypical antipsychotics induced weight change in elderly patients. Part 2 was to determine whether certain atypical antipsychotics induced more weight change in elderly patients.Methods:In Part 1, a retrospective chart review was done on 115 geriatric inpatients. After exclusion, patients were divided into four groups: control (n = 17), new treatment (n = 18), long-term treatment (n = 13), and medication switch groups (n = 8). In Part 2, a retrospective medication review was performed on 169 geriatric inpatients. After exclusion, patients were divided into three groups: aripiprazole (n = 18), olanzapine (n = 49), and risperidone (n = 57). Body weights were obtained at two different time points.Results:No significant difference in weigh...

【 授权许可】

CC BY