Prognostic Value of Initial Assessment of Residual Hypoventilation Using Nocturnal Capnography in Mechanically Ventilated Neuromuscular Patients: A 5-Year Follow-up Study

Frontiers in Medicine

Adam Ogna¹ 

关键词: home mechanical ventilation;    neuromuscular disease;    restrictive respiratory failure;    nocturnal hypoventilation;    transcutaneous capno-oximetry;    prognosis;   

DOI  :  10.3389/fmed.2016.00040

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

BackgroundRestrictive respiratory failure is a major cause of morbidity and mortality in neuromuscular diseases (NMD). Home mechanical ventilation (HMV) is used to treat hypoventilation, and its efficiency is mostly assessed by daytime blood gases or nocturnal oxygen saturation monitoring (SpO2). Non-invasive transcutaneous measure of CO2 (TcCO2) allows to directly assess nocturnal hypercapnia and to detect residual hypoventilation with a higher sensitivity than SpO2. We aimed to compare the prognostic value of nocturnal SpO2 and TcCO2 in ventilated adult NMD patients.

【 授权许可】

CC BY