Determinants and prognosis of high-sensitivity cardiac troponin T peak plasma concentration in patients hospitalized for non-cardiogenic shock:

SAGE Open Medicine

MarieCaujolle¹ 

关键词: High-sensitivity cardiac troponin T;    determinants;    mortality;    shock;   

DOI  :  10.1177/2050312118771718

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Purpose:The aim of this study was to assess the determinants and prognostic value of high-sensitivity cardiac troponin T peak plasma concentration in intensive care unit patients with non-cardiogenic shock.Material and methods:A prospective observational cohort study was conducted in a single intensive care unit between November 2014 and December 2015.Results:During the study period, 206 patients were hospitalized in the intensive care unit for non-cardiogenic shock and the median peak high-sensitivity cardiac troponin T was 55.1 [24.5–136] pg/mL. A multivariate analysis combining all variables showed that higher body mass index (t = 2.52, P = 0.01), lower left ventricular systolic function (t = −2.73, P = 0.007), higher white blood cell count (t = 3.72, P = 0.0001), lower creatinine clearance (t = −2.84, P = 0.0005), higher lactate level (t = 2.62, P = 0.01) and ST-segment depression (t = 3.98, P = 0.0001) best correlated with log10-transformed high-sensitivity cardiac troponin T peak plasma concentratio...

【 授权许可】

CC BY