Treatment of Cirrhosis-Associated Hyponatremia with Midodrine and Octreotide

Frontiers in Medicine

Sharad Patel¹ 

关键词: sodium;    hyponatremia;    cirrhosis;    midodrine;    octreotide;   

DOI  :  10.3389/fmed.2017.00017

学科分类：医学（综合）

来源: Frontiers

【 摘 要 】

BackgroundHyponatremia in the setting of cirrhosis is a common electrolyte disorder with few therapeutic options. The free water retention is due to non-osmotic vasopressin secretion resulting from the cirrhosis-associated splanchnic vasodilatation. Therefore, vasoconstrictive therapy may correct this electrolyte abnormality. The aim of this study was to assess the efficacy of midodrine and octreotide as a therapeutic approach to increasing urinary electrolyte-free water clearance (EFWC) in the correction of cirrhosis-associated hyponatremia.

【 授权许可】

CC BY