Review of Literature: Genes Related to Postaxial Polydactyly

Frontiers in Pediatrics

Prashant Kumar Verma¹ 

关键词: postaxial polydactyly;    molecular approach;    hedgehog protein;    sonic hedgehog;    signal pathways;    gene;    cilia;    investigation;    approach;   

DOI  :  10.3389/fped.2015.00008

学科分类：儿科学

来源: Frontiers

【 摘 要 】

Background: Postaxial polydactyly (PAP) is one of the commonest congenital malformations and usually is associated to several syndromes. There is no primary investigational strategy for PAP cases with single gene disorder in literature. PAP cases with single gene disorder can be classified according to common pathways and molecular basis. Molecular classification may help in diagnostic approach.

【 授权许可】

CC BY