Failure of the Anticoagulant Therapy and Psychological Distress: Still Far From a Bridge

Frontiers in Psychology

Federica Galli¹ 

关键词: anticoagulant therapy;    failure;    anxiety;    depression;    stress;   

DOI  :  10.3389/fpsyg.2018.01709

学科分类：心理学（综合）

来源: Frontiers

【 摘 要 】

Background: The procoagulant stress response reflects part of a beneficial adaptation of the organism to environmental threats, but a protracted procoagulant state generates a thrombotic risk. Atrial fibrillation (AF) is the most common arrhythmia in the general population. Patients with AF have a higher risk of thromboembolic events and stroke, therefore they are treated with long-term oral anticoagulant (OAC) therapy. The aim of this study is to evaluate if there is any association between psychological distress and clinically unexplained variations of the International Normalized Ratio (INR), that is the index used to monitor both thromboembolic and bleeding risk in the case of patients under OAC therapy.

【 授权许可】

CC BY