Molybdenum Nutriture in Humans:

Journal of Evidence-Based Integrative Medicine

Janet A.Novotny¹ 

关键词: bioavailability;    cofactor;    hyperuricemia;    mineral;    molybdenum;    molybdopterin;    nutrition;    sulfite oxidase;   

DOI  :  10.1177/2156587211406732

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Molybdenum is a trace element that functions as a cofactor for at least 4 enzymes: sulfite oxidase, xanthine oxidase, aldehyde oxidase, and mitochondrial amidoxime reducing component. In each case, molybdenum is bound to a complex, multiring organic component called molybdopterin, forming the entity molybdenum cofactor. The best sources of dietary molybdenum are legumes, grains, and nuts. Bioavailability of molybdenum is fairly high but depends on form, with molybdenum preparations having greater bioavailability than food-bound molybdenum. Molybdenum deficiency and toxicity are rare, possibly because of the body’s ability to adapt to a wide range of molybdenum intake levels. At low intakes of molybdenum, the fractional transfer of molybdenum from plasma to urine is lower and a greater fraction is deposited into tissues, and at high intakes of molybdenum, the opposite occurs. Molybdenum has proven to be an interesting trace mineral that is essential for life.

【 授权许可】

CC BY-NC