Optimization of supercritical fluid extraction of geniposidic acid from plantain seeds using response surface methodology

Green Chemistry Letters and Reviews

Jiadan Wang¹ 

关键词: geniposidic acid;    supercritical fluid extraction;    Box–Behnken design;    optimization;    plantain seeds;   

DOI  :  10.1080/17518253.2014.949876

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

The process parameters of supercritical CO2 (SCCO2) plus modifer for the extraction of geniposidic acid from plantain seeds were studied using a Box–Behnken design. The effects of independent variables, that is, ethanol concentration (0–70%, ethanol:water, v/v), extraction pressure (10–30 MPa), and temperature (50–80°C) on the yield of geniposidic acid were evaluated. Results indicated that the data could be well fitted to a second-order polynomial model. The effects of ethanol concentration and temperature, as well as the interaction between ethanol concentration and temperature were significant (p < 0.05). The yield (8.9 mg/g) of modified SCCO2 extraction at optimal conditions was compared with that obtained by Soxhlet extraction or ultrasound assisted extraction.

【 授权许可】

Unknown