Analisi di Budget Impact di Ticagrelor nel Trattamento di Prevenzione in Pazienti con Sindrome Coronarica Acuta:

Global & Regional Health Technology Assessment

Gian PieroPerna¹ 

关键词: ACS;    Budget impact;    Cost;    Ticagrelor;   

DOI  :  10.5301/grhta.5000255

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Budget impact analysis of ticagrelor for preventive treatment of patients with acute coronary syndromesBackgroundTicagrelor 90 mg BID is indicated for the prevention of thrombotic cardiovascular events in patients with acute coronary syndromes (ACS). Outcomes from the PLATO trial demonstrated that ticagrelor + ASA reduced the rate of a combined endpoint of cardiovascular death, myocardial infarction, or stroke compared to clopidogrel + ASA.ObjectiveThis analysis estimated the budget impact of the use of ticagrelor and clopidogrel for the prevention of thrombotic cardiovascular events in patients with ACS in Italy, based on the PLATO trial results.MethodsA budget-impact model (BIM) was developed to estimate the direct costs up to 12 months after an ACS event from the Italian NHS perspective. Resource utilization (drugs, screening, monitoring, hospitalizations and transfusions) was derived from the PLATO trial. Only direct medical costs were considered. Ex-factory prices (including all discounts) and Nation...

【 授权许可】

CC BY