Effects of Cryopreserved Amniotic Membrane Allograft on Total Ankle Arthroplasty Wound Healing:

Foot & Ankle Orthopaedics

ThomasBemenderfer¹ 

关键词: Total ankle arthroplasty;    orthobiologics;    regenerative adjuncts;    ankle arthritis;    wound complications;   

DOI  :  10.1177/2473011417S000027

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Category:Ankle, Ankle Arthritis, Basic Sciences/BiologicsIntroduction/Purpose:Despite improvements in newer-generation total ankle arthroplasty (TAA) implants, relatively high wound-healing complication rates continue to be reported with the anterior ankle incision. Only 66% heal without wound-healing complications, 25% have minor complications requiring local care and/or oral antibiotics, and 9% experience major complications requiring reoperation (Raikin et al., 2010). Recently, multiple regenerative adjuncts have been investigated to reduce postoperative complications by enhancing local healing factors and reducing risk of infection. The relatively novel use of adjunctive therapy utilizing cryopreserved amniotic membrane modulate wound healing by down-regulating inflammation and scar formation (Hanselman et al., 2015). The purpose of our study is to determine whether the local application of cryopreserved amniotic membrane wound allograft may enhance soft tissue wound healing of the TAA anterior ankle ...

【 授权许可】

CC BY