A mild, simple, and efficient approach to the synthesis of some novel 7-benzylidene-2,3-diphenyl-3,3a,4,5,6,7-hexahydro-2H-indazole derivatives

Green Chemistry Letters and Reviews

Gholam Hossein Mahdavinia¹ 

关键词: indazole;    α;    ά-bis(substituted-arylidene)cycloalkanones;    DABCO;    solvent-free;   

DOI  :  10.1080/17518253.2014.976280

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

The aldol condensation of various aromatic aldehydes with cycloalkanones using ethanolic KOH afforded α,ά-bis (substituted-arylidene) cycloalkanones in excellent yields. The cyclization of the resulting cycloalkanones with phenyl hydrazine in the presence of catalytic amounts of DABCO (1,4-diazabicyclo[2.2.2]octane) under solvent-free conditions afforded 7-benzylidene-2,3-diphenyl-3,3a,4,5,6,7-hexahydro-2H-indazole derivatives in good to excellent yields.

【 授权许可】

Unknown