Water mediated synthesis of various [1,3]oxazine compounds using alum as a catalyst

Green Chemistry Letters and Reviews

Sandip A. Sadaphal¹ 

关键词: [1;    3]oxazine;    water;    β-napthol/α-naphthol;    formaldehyde;    aromatic amine;   

DOI  :  10.1080/17518251003709522

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

A simple, efficient, and practical procedure for the synthesis of various substituted 2,3-dihydro-2-phenyl-1H-naphtho[1,2-e][1,3]oxazines and 3,4-dihydro-3-phenyl-2H-naphtho[2,1-e][1,3]oxazines using KAl(SO4)2 12H2O (alum) as a non-toxic, reusable, inexpensive, and easily available catalyst is described using water as a solvent. These improved reaction conditions allow the preparation of a wide variety of substituted [1,3]oxazines in high yields and purity under mild reaction conditions.

【 授权许可】

Unknown