An efficient synthesis of imidazo[2,1-b][1,3]thiazins via a one-pot, three-component and solvent-free reaction

Green Chemistry Letters and Reviews

Mohammad Mehdi Ghanbari¹ 

关键词: Thiohydantoin;    dimedone;    aldehyde;    multi-component reactions;    solvent-free;   

DOI  :  10.1080/17518253.2016.1231841

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

A simple and eco-friendly method for the synthesis of novel imidazo[2,1-b][1,3]thiazin derivatives has been developed via the one-pot, three-component and solvent-free reaction of thiohydantoins, aromatic aldehyde and 5,5-dimethylcyclohexane-1,3-dione in the presence of catalytic amount of p-toluene sulfonic acid, in good and excellent yields.

【 授权许可】

Unknown