Anaesthesia and sleep: Where are we now?

Clinical and Translational Neuroscience

ThomasGent¹ 

关键词: Sleep;    general anaesthesia;    thalamus;    hypothalamus;    translational medicine;    animal models;    human;    neocortex;   

DOI  :  10.1177/2514183X17726281

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

The mechanisms regulating the control of consciousness in both spontaneous sleep–wake behaviour and general anaesthesia remain poorly understood and are a fundamental question in neuroscience. The last 30 years have identified numerous molecular substrates and more recently important monoaminergic neuronal substrates. Future work now needs to concentrate on elucidating the convergence of these neuronal circuits to build a unifying mechanism of consciousness control.

【 授权许可】

CC BY