Global & Regional Health Technology Assessment | |
Mortality Cost of Duchenne Muscular Dystrophy: | |
ErikLandfeldt1  | |
关键词: Cost of illness; Health policy; Neuromuscular diseases; | |
DOI : 10.5301/grhta.5000260 | |
学科分类:医学(综合) | |
来源: Sage Journals | |
【 摘 要 】
BackgroundDespite advances in management and care, Duchenne muscular dystrophy (DMD) remains universally fatal. The objective of this study was to estimate the mortality cost of DMD.MethodsWe estimated the mean total national annual mortality cost associated with DMD by simulating the mean number of patients who would have been alive in 2012 in the absence of DMD using data on the mean DMD incidence, mean number of live male births, mean life expectancy at birth in DMD and the male general population, and a societal willingness-to-pay (WTP) for a life-year. We attributed each patient who would have been alive in 2012 a lost life-year. Finally, to estimate the mean mortality cost of DMD, we multiplied the estimated mean number of life-years lost with a societal WTP for a life-year of €75,000.ResultsThe mean total number of patients who would have been alive in 2012 in the absence of DMD was estimated at 4470 (95% bootstrapped CI: 4449-4492) in Germany, 3313 (3297-3329) in Italy, 3564 (3547-3581) in the UK,...
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201901210914482ZK.pdf | 186KB | download |