Efficacy of the Hydroalcoholic Extract of Tribulus terrestris on the Serum Glucose and Lipid Profile of Women With Diabetes Mellitus: A Double-Blind Randomized Placebo-Controlled Clinical Trial

Journal of Evidence-Based Integrative Medicine

Nasrin BabadaeiSamani¹ 

关键词: diabetes mellitus;    Tribulus terrestris;    herbal medicine;    traditional medicine;   

DOI  :  10.1177/2156587216650775

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Aim.Considering traditional use of Tribulus terrestris in diabetes and proven antihyperglycemic and antihyperlipidemic effects of T terrestris in animal studies, we aimed to evaluate the efficacy of the hydroalcoholic extract of T terrestris on the serum glucose and lipid profile of women with non–insulin-dependent diabetes mellitus.Methods.Ninety-eight women with diabetes mellitus type 2 were randomly allocated to receive the T terrestris (1000 mg/d) or placebo for 3 months. The patients were evaluated in terms of the fasting blood glucose, 2-hour postprandial glucose, glycosylated hemoglobin, and lipid profile.Results.Tribulus terrestris showed a significant blood glucose–lowering effect in diabetic women compared to placebo (P < .05). Also, the total cholesterol and low-density lipoprotein of T terrestris group was significantly reduced compared with placebo, while no significant effect was observed in the triglyceride and high-density lipoprotein levels.Conclusions.The study showed preliminary promisi...

【 授权许可】

CC BY-NC