N-heterocyclic carbene (thiamine) promoted eco-friendly synthesis of quinoxalines under mild reaction conditions

Green Chemistry Letters and Reviews

Sarita Singh¹ 

关键词: quinoxaline;    phenacyl bromide;    phenylenediamine;    thiamine;    N-heterocyclic carbene;   

DOI  :  10.1080/17518253.2012.681706

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

An efficient and convenient protocol of broad scope for the synthesis of quinoxaline by cyclization-oxidation of phenacyl bromide with equimolar amount of phenylenediamine at room temperature catalyzed by thiamine in the form of N-heterocyclic carbene (NHC). High efficiency, inexpensiveness, and non-toxicity are the interesting features of the catalyst, which make it eco-friendly and highly attractive.

【 授权许可】

Unknown