Protein-Losing Enteropathy Associated With Egg Allergy in a 5-Month-Old Boy

Journal of Investigational Allergology and Clinical Immunology

N Kondo¹  H Kaneko¹  T Teramoto¹  M Aoki¹  N Kawamoto¹  K Omoya¹  T Fukao¹  M Kondo¹ 

[1] N Kondo

关键词: Food challenge;    Egg allergy;    Hypocalcemia;    Protein-losing enteropathy (PLE);   

Others  :  1184739

【 摘 要 】

Protein-losing enteropathy (PLE), the manifestation of a diverse set of disorders, is characterized by excessive loss of plasma proteins intothe affected portions of the gastrointestinal tract, and this results in hypoalbuminemia. A 5-month-old breastfed boy presented severe PLEwith hypogammaglobulinemia, hypocalcemia, and hypomagnesemia induced by an egg allergy. He developed hypocalcemic convulsions.The diagnosis of PLE was confi rmed by elevated fecal 1-antitrypsin clearance and a positive fi nding on a protein-losing scintigram. Hisallergy to egg delivered through maternal milk was confi rmed as the cause of PLE, since the mother’s elimination of egg from her dietimproved his condition and maternal egg challenge provoked symptoms of diarrhea, vomiting, and elevated 1-antitrypsin clearance. Atthe time of writing, he is 22 months old and has experienced no further episodes after the elimination of egg-containing food.