Resting energy expenditure and carbohydrate oxidation are higher in elderly patients with COPD: a case control study

Nutrition Journal

Luciene de Souza Venâncio¹  Maurício Longo Galhardo²  Márcia Maria Faganello²  Darlan Muller Nakato²  Kátia Cristina Portero McLellan³  Gustavo Duarte Pimentel⁵  Erick Prado de Oliveira⁴  Bruna Rubi Ramires¹ 

[1] Universidade Metodista de Piracicaba (UNIMEP), Lins, SP, Brazil;Department of Physiotherapy, Centro Universitário Católico Salesiano Auxilium-Unisalesiano, Lins, SP, Brazil;Department of Public Health, Centre for Physical and Nutritional Metabolism (CeMENutri), São Paulo State University (UNESP), Botucatu, SP, Brazil;CeMENutri - Faculdade de Medicina, Depto. de Saúde Pública (FMB - UNESP), Distrito de Rubião Jr, s/n°, 18.618-970, Botucatu, SP, Brazil;Department of Internal Medicine, Campinas State University (UNICAMP), Campinas, SP, Brazil

关键词: Carbohydrate oxidation;    Elderly;    Resting energy expenditure;    Chronic obstructive pulmonary disease;   

Others  :  824319
DOI  :  10.1186/1475-2891-11-37

 received in 2012-01-11, accepted in 2012-05-31,  发布年份 2012

【 摘 要 】

Background

Elderly patients with chronic obstructive pulmonary disease (COPD) usually have a compromised nutritional status which is an independent predictor of morbidity and mortality. To know the Resting Energy Expenditure (REE) and the substrate oxidation measurement is essential to prevent these complications. This study aimed to compare the REE, respiratory quotient (RQ) and body composition between patients with and without COPD.

Methods

This case–control study assessed 20 patients with chronic obstructive pulmonary disease attending a pulmonary rehabilitation program. The group of subjects without COPD (control group) consisted of 20 elderly patients attending a university gym, patients of a private service and a public healthy care. Consumption of oxygen (O₂) and carbon dioxide (CO₂) was determined by indirect calorimetry and used for calculating the resting energy expenditure and respiratory quotient. Body mass index (BMI) and waist circumference (WC) were also measured. Percentage of body fat (%BF), lean mass (kg) and muscle mass (kg) were determined by bioimpedance. The fat free mass index (FFMI) and muscle mass index (MMI) were then calculated.

Results

The COPD group had lower BMI than control (p = 0.02). However, WC, % BF, FFMI and MM-I did not differ between the groups. The COPD group had greater RQ (p = 0.01), REE (p = 0.009) and carbohydrate oxidation (p = 0.002).

Conclusions

Elderly patients with COPD had higher REE, RQ and carbohydrate oxidation than controls.

【 授权许可】

   
2012 Ramires et al.; licensee BioMed Central.

【 图 表 】

Figure 1.

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