Hypothermia: effects on platelet function and hemostasis

Thrombosis Journal

Marcus Lancé²  Abraham Emanuel Marcus²  Kris Stevens²  Sven Van Poucke¹ 

[1] Department of Anesthesiology, Intensive Care Medicine, Emergency Care and Pain Therapy ZOL, Genk, Belgium;Department of Anesthesiology, Maastricht University, Maastricht, Netherlands

关键词: Hemostasis;    Coagulation;    Hypothermia;    Platelets;   

Others  :  1135343
DOI  :  10.1186/s12959-014-0031-z

 received in 2014-09-21, accepted in 2014-11-30,  发布年份 2014

【 摘 要 】

Mild therapeutic hypothermia is considered standard care in the treatment of patients resuscitated from cardiac arrest. With increasingly more frequent concomitant use of platelet-inhibiting drugs, clinicians must be cognizant of the ramifications of hypothermia on platelet function as part of hemostasis. The effects of hypothermia on platelet function have been studied for more than 50 years, but the results are inconsistent and may be related to the circumstances during which hypothermia is achieved. This review summarizes current knowledge of platelet function during hypothermia and the impact on hemostasis.

【 授权许可】

   
2014 Van Poucke et al. ; licensee BioMed Central Ltd.

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