Acute lung injury and the acute respiratory distress syndrome in the injured patient

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Maureen McCunn²  Brandon Bruns¹  Magdalena Bakowitz² 

[1] Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA;Department of Anesthesiology & Critical Care, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA

关键词: Airway pressure release ventilation (APRV);    High-frequency oscillatory ventilation (HFOV);    Flail chest;    Rib open reduction internal fixation;    Rib plating;    Extracorporeal membrane oxygenation (ECMO);    Prone positioning;    Injury;    Trauma;    Acute respiratory distress syndrome (ARDS);    Acute lung injury (ALI);    Lung injury;   

Others  :  826434
DOI  :  10.1186/1757-7241-20-54

 received in 2012-02-08, accepted in 2012-06-11,  发布年份 2012

【 摘 要 】

Acute lung injury and acute respiratory distress syndrome are clinical entities of multi-factorial origin frequently seen in traumatically injured patients requiring intensive care. We performed an unsystematic search using PubMed and the Cochrane Database of Systematic Reviews up to January 2012. The purpose of this article is to review recent evidence for the pathophysiology and the management of acute lung injury/acute respiratory distress syndrome in the critically injured patient. Lung protective ventilation remains the most beneficial therapy. Future trials should compare intervention groups to controls receiving lung protective ventilation, and focus on relevant outcome measures such as duration of mechanical ventilation, length of intensive care unit stay, and mortality.

【 授权许可】

   
2012 Bakowitz et al.; licensee BioMed Central Ltd.

【 图 表 】

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