Optimal surgical extent of lateral and central neck dissection for papillary thyroid carcinoma located in one lobe with clinical lateral lymph node metastasis

World Journal of Surgical Oncology

Kyung Tae¹  You Hern Ahn²  Woong Hwan Choi²  Jin Hyeok Jeong¹  Jong Min Kim¹  Yong Bae Ji¹  Hyo Sub Keum¹ 

[1] Departments of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 133-792, Korea;Department of Internal Medicine, College of Medicine, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 133-792, Korea

关键词: Central neck dissection;    Lymph node metastasis;    Lateral neck dissection;    Papillary thyroid carcinoma;   

Others  :  827080
DOI  :  10.1186/1477-7819-10-221

 received in 2012-08-10, accepted in 2012-10-15,  发布年份 2012

【 摘 要 】

Background

The indications and extent of cervical lymph node dissection in papillary thyroid carcinoma (PTC) are still being debated. The aim of this study was to analyze the patterns of cervical lymph node metastasis in the lateral and central compartment and related factors and suggest the optimal extent of lateral and central neck dissection for PTC patients with clinical lateral lymph node metastasis.

Methods

We retrospectively analyzed 72 patients with unilateral PTC who underwent therapeutic lateral neck dissections with concomitant total thyroidectomy and central neck dissection between January 2001 and December 2009.

Results

The 72 patients underwent 79 sides of therapeutic lateral neck dissection. The most frequent metastatic level in the ipsilateral lateral compartment was level IV (75.0%), followed by level III (69.4%), level II (56.9%) and level V (20.8%). Multiple level metastases were common (77.8%) and were correlated with tumor size (≥ 10 mm). The central compartment lymph node metastasis rate was 87.5%, including 26.4% of contralateral central compartment metastases.

Conclusion

In PTC patients with clinical lateral lymph node metastasis, the optimal extent of lateral and central neck dissection should include levels II, III, IV and V as well as the bilateral central compartment.

【 授权许可】

   
2012 Keum et al.; licensee BioMed Central Ltd.

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