期刊论文详细信息
| World Allergy Organization Journal | |
| Severity of allergic rhinitis and asthma development in children | |
| Alberto Verrotti3  Franco Frati1  Serena Buttafava1  Giorgio Ciprandi2  Ilaria Bizzarri3  Elisa Panfili3  Arianna Latini3  Alessia Carelli3  Giuseppe Di Cara3  | |
| [1] Medical and Scientific Department, Stallergenes Italy, Milan, Italy;Medicine Department, IRCCS-A.O.U. San Martino, Viale Benedetto XV 6, Genoa, 16132, Italy;Institute of Pediatrics, Department of Surgical and Biomedical specialty, Perugia, Italy | |
| 关键词: Children; Severity; Asthma; Allergic rhinitis; | |
| Others : 1180920 DOI : 10.1186/s40413-015-0061-4 |
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| received in 2014-12-12, accepted in 2015-02-06, 发布年份 2015 | |
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【 摘 要 】
Allergic rhinitis (AR) is a relevant risk factor for the development of asthma in children. We recruited a cohort of 104 children with AR and re-evaluated them after 5 years. We considered the ARIA classification. All patients, who had moderate to severe persistent AR at baseline, developed asthma symptoms. These results strongly indicate that the severity of AR may be an important factor that increases the risk of asthma development in children.
【 授权许可】
2015 Di Cara et al.; licensee BioMed Central.
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| 20150514102009724.pdf | 1039KB | ||
| Figure 1. | 39KB | Image |
【 图 表 】
Figure 1.
【 参考文献 】
- [1]Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the world health organization, GA2LEN and AllerGen). Allergy. 2008;63 Suppl 86:8–160.
- [2]Deliu M, Belgrave D, Simpson A, Murray CS, Kerry G, Custovic A. Impact of rhinitis on asthma severity in school-age children. Allergy. 2014. doi:10.1111/all.12467.
- [3]Ciprandi G, Signori A, Tosca MA, Cirillo I. Spirometric abnormalities in patients with allergic rhinitis: indicator of an asthma march? Amer J Rhinol Allergy. 2011;32:22–8.
- [4]Global Initiative for Asthma. GINA guidelines. Global strategy for Asthma Management and Prevention. 2014. Available at: http://www.ginasthma.org/ Accessed on March 2015.
- [5]Ciprandi G, Cirillo I. The lower airway pathology of rhinitis. J Allergy Clin Immunol. 2006;118:1105–9.
- [6]Amorim MM, Araruna A, Caetano LB, Cruz AC, Santoro LL, Fernandes LG. Nasal eosinophilia: an indicator of eosinophilic inflammation in asthma. Clin Exp Allergy. 2010;40:867–74.
- [7]McMillan SJ, Lloyd CM. Prolonged allergen challenge in mice leads to persistent airway remodelling. Clin Exp Allergy. 2004;34:497–507.
- [8]Lambrecht BN, Hammad H. Asthma: the importance of dysregulated barrier immunity. Eur J Immunol. 2013;43:3125–37.
- [9]Jõgi R, Janson C, Björnsson E, Boman G, Björkstén B. The prevalence of asthmatic respiratory symptoms among adults in Estonian and Swedish university cities. Allergy. 1996;51(5):331–6.
- [10]Bugiani M, Carosso A, Migliore E, Piccioni P, Corsico A, Olivieri M, et al. Allergic rhinitis and asthma comorbidity in a survey of young adults in Italy. Allergy. 2005;60(2):165–70.
- [11]de Marco R, Cappa V, Accordini S, Rava M, Antonicelli L, Bortolami O, et al. Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010. Eur Respir J. 2012;39(4):883–92.
- [12]Bjerg A, Ekerljung L, Middelveld R, Dahlén SE, Forsberg B, Franklin K, et al. Increased prevalence of symptoms of rhinitis but not of asthma between 1990 and 2008 in Swedish adults: comparisons of the ECRHS and GA2LEN surveys. PLoS One. 2011;6(2):e16082.
- [13]Johannessen A, Verlato G, Benediktsdottir B, Forsberg B, Franklin K, Gislason T, et al. Longterm follow-up in European respiratory health studies - patterns and implications. BMC Pulm Med. 2014;14:63.
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