Development of interactive algorithm for clinical management of acute events related to sickle cell disease in emergency department

Orphanet Journal of Rare Diseases

Lucia De Franceschi³  Maria Domenica Cappellini⁵  Oliviero Olivieri³  Silverio Perrotta⁶  Paolo Rigano¹  Manuela Balocco²  Giovanna Graziadei⁵  Gabriele Finco⁴  Gian Luca Forni² 

[1]Department of Hematology and Oncology, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy

[2]Department of Medicine, Section of Haematology, Ospedale Galliera, Genova, Italy

[3]Department of Medicine, Section of Internal Medicine, University of Verona-AOUI-Verona, Verona, Italy

[4]Department of Medical Science “M. Aresu”, Section of Anesthesia, Intensive Care and Pain Therapy

[5] University of Cagliari, Cagliari, Italy

[6]Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy

[7]Department of Pediatrics, Second University of Naples, Napoli, Italy

关键词: Pain;    Emergency departments;    Acute vaso-occlusive crisis;    Sickle cell disease;   

Others  :  1150338
DOI  :  10.1186/1750-1172-9-91

 received in 2014-05-08, accepted in 2014-06-11,  发布年份 2014

【 摘 要 】

Sickle cell disease (SCD ORPHA232; OMIM 603903) is a rare hereditary red cell disorder, which global distribution is changed in the last decade due to immigration-fluxes from endemic areas to Western-countries. One of the main clinical manifestations of SCD are the acute painful vaso-occlusive crisis, which cause frequent accesses of SCD patients to the emergency departments (EDs). This has generated the requirement of feasible tools for emergency givers. In the context of the scientific-Italian-Society for the study of Thalassemias and Hemoglobinopathies (SITE), we developed an algorithm with interactive windows to guide physicians in managing SCD patients in EDs.

【 授权许可】

   
2014 Forni et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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