An in-vitro animal experiment on metal implants’ thermal effect on radiofrequency ablation

World Journal of Surgical Oncology

Jian Kong²  Lu-Ping Wang²  Fan He²  Hong Chu¹  Zhen-Wen Lin² 

[1] Department of Gynecology, Shenzhen Second People’s Hospital, Shenzhen, 3002 Sungang West Road, Futian district, Shenzhen, Guangdong 518035, People’s Republic of China;Minimally Invasive Interventional Treatment Center, Shenzhen People’s Hospital, Shenzhen, Guangdong, People’s Republic of China

关键词: In vitro;    Animal experiment;    Thermal effect;    Radiofrequency ablation;    Metal;    Implant;   

Others  :  823766
DOI  :  10.1186/1477-7819-11-147

 received in 2013-01-08, accepted in 2013-06-14,  发布年份 2013

【 摘 要 】

Background

To explore metal implants’ thermal effect on radiofrequency ablation (RFA) and ascertain distance-thermal relationship between the metal implants and radiofrequency (RF) electrode.

Methods

Metal implants models were established in seven in-vitro porcine livers using silver clips or ¹²⁵I seeds. RFA were conducted centering the RF electrode axis1 cm away from them, with one side containing a metal implants model the test group and the other side the control group. The thermometric needles were used to measure multi-point temperatures in order to compare the time-distance-temperature difference between the two groups. The gross scopes of the ablation of the two groups were measured and the tissues were analyzed for microscopic histology.

Results

At the ablation times of 8, 12, and 15 min, the average multi-point temperatures of the test group and the control group were 48.2±18.07°C, 51.5±19.57°C, 54.6±19.75°C, and 48.6±17.69°C, 52.2±19.73°C, 54.9±19.24°C, respectively, and the differences were not statistically significant (n=126, P>0.05). At the ablation times of 12 and 15 min, the ablation scopes of the test group and the control group were (horizontal/longitudinal diameter) 1.55/3.48 cm, 1.89/3.72 cm, and 1.56/3.48 cm, 1.89/3.72 cm, respectively, and the differences were not statistically significant (n=14, P>0.05). The two groups had the same manifestations in microscopy.

Conclusions

Metal implants do not cause significant thermal effect on RFA.

【 授权许可】

   
2013 Lin et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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