期刊论文详细信息
Nutrition Journal
Use of food frequency questionnaire to assess relationships between dietary habits and cardiovascular risk factors in NESCAV study: validation with biomarkers
Michèle Guillaume3  Adelin Albert3  Ala’a Alkerwi1  Nicolas Sauvageot2 
[1] CRP-Santé, Department of Public Health, 1A rue Thomas Edison, L-1445 Strassen, Luxembourg;CRP-Santé, CCMS (Competence center in methodology and statistics), 1A rue Thomas Edison, L-1445 Strassen, Luxembourg;Ecole de Santé Publique, Université de Liège, Liège, Belgium
关键词: NESCAV;    Biomarkers;    Cardiovascular risk;    Validation;    Food frequency questionnaire;   
Others  :  803275
DOI  :  10.1186/1475-2891-12-143
 received in 2013-02-25, accepted in 2013-10-26,  发布年份 2013
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【 摘 要 】

Background

Validation of Food frequency questionnaire (FFQ) is particularly important element, as incorrect information may lead to false associations between dietary factors and diseases. The aim of the study was to evaluate the validity of the FFQ used in NESCAV (Nutrition, Environment and Cardiovascular Health) study, by comparing the estimated intakes of fruits and vegetables and of several micro-nutrients with corresponding nutritional biomarkers.

Methods

Relative validity was assessed in a sample of 922 subjects (452 men and 470 women). Comparisons between FFQ-estimates and their corresponding biomarkers were performed through correlation and cross classification into quintiles by using both crude and energy-adjusted FFQ-estimates. Correlations adjusted for confounders were also computed. All analyses were performed separately for men and women.

Results

Concerning micro-nutrients, significant correlations were found for vitamin B9, D, E, B12 β-carotene and iodine in both men and women. Energy-adjustment led to an increase of all correlations cited previously. However, after excluding supplement users, correlations for vitamin D were not significant anymore. Concerning fruits and vegetables, all correlations were significant. Vegetables alone and fruits and vegetables correlated better in men (r around 0.2) than in women (r around 0.1). In men, correlation was also better for vegetables alone and fruits and vegetables than fruits alone.

Conclusion

These data demonstrate that this FFQ is a reasonable tool to assess intakes of fruits and vegetables and of several micro-nutrients. We conclude that our FFQ is suitable to be used in NESCAV study, although protein and vitamin D estimates should be interpreted with caution.

【 授权许可】

   
2013 Sauvageot et al.; licensee BioMed Central Ltd.

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