期刊论文详细信息
Nutrition Journal
The impact of iodine supplementation and bread fortification on urinary iodine concentrations in a mildly iodine deficient population of pregnant women in South Australia
Basil Hetzel4  Gary Ma2  Ted Nettelbeck3  Rachel Roberts3  David J Torpy5  Paul A Fogarty3  Nicolette A Hodyl4  Vicki L Clifton1 
[1] Robinson Institute, Lyell McEwin Hospital, Haydown Rd, Elizabeth Vale, SA, 5112, Australia;International Council for Control of Iodine Deficiency Disorders Global Network (ICCIDD), Westmead Hospital, Westmead, NSW, Australia;School of Psychology, University of Adelaide, Adelaide, SA, Australia;Robinson Institute, University of Adelaide, Adelaide, SA, Australia;Department of Endocrinology, University of Adelaide, Adelaide, SA, Australia
关键词: Supplements;    Urine;    Pregnancy;    Iodine;   
Others  :  811230
DOI  :  10.1186/1475-2891-12-32
 received in 2012-11-06, accepted in 2013-03-08,  发布年份 2013
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【 摘 要 】

Mild iodine deficiency during pregnancy can have significant effects on fetal development and future cognitive function. The purpose of this study was to characterise the iodine status of South Australian women during pregnancy and relate it to the use of iodine-containing multivitamins. The impact of fortification of bread with iodized salt was also assessed. Women (n = 196) were recruited prospectively at the beginning of pregnancy and urine collected at 12, 18, 30, 36 weeks gestation and 6 months postpartum. The use of a multivitamin supplement was recorded at each visit. Spot urinary iodine concentrations (UIC) were assessed. Median UICs were within the mildly deficient range in women not taking supplements (<90 μg/L). Among the women taking iodine-containing multivitamins UICs were within WHO recommendations (150–249 μg/L) for sufficiency and showed an increasing trend through gestation. The fortification of bread with iodized salt increased the median UIC from 68 μg/L to 84 μg/L (p = .011) which was still in the deficient range. Pregnant women in this region of Australia were unlikely to reach recommended iodine levels without an iodine supplement, even after the mandatory iodine supplementation of bread was instituted in October 2009.

【 授权许可】

   
2013 Clifton et al.; licensee BioMed Central Ltd.

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