Impact of gender on COPD expression in a real-life cohort

Respiratory Research

Pierre-Régis Burgel⁷  Jean-Louis Paillasseur^1,11  Gilles Jebrak⁶  Christophe Pinet³  Pascal Chanez¹  Thierry Perez^1,13  Roger Escamilla⁹  Pascale Surpas²  Pascale Nesme-Meyer^1,12  Isabelle Court-Fortune⁸  Graziella Brinchault⁴  Denis Caillaud^1,10  Gaetan Deslée⁵  Nicolas Roche⁷ 

[1] Département des Maladies Respiratoires, AP-HM, Université de la Méditerranée, Marseille, France;Centre Médical de Bayère, Charnay, France;Clinique des Fleurs, Ollioules, France;Service de Pneumologie, Hôpital Pontchaillou, Rennes, France;Service de Pneumologie, Hôpital Maison Blanche, CHU de Reims, Reims, France;Service de Pneumologie, Hôpital Bichat, AP-HP, Paris, France;Service de Pneumologie et Soins Intensifs Respiratoires, Groupe Hospitalier Cochin Broca Hôtel-Dieu, AP-HP and Université Paris Descartes, Sorbonne Paris Cité, Paris, France;Service de Pneumologie, CHU Saint Etienne, Saint Etienne, France;Clinique des voies respiratoires Hopital Larrey, Toulouse, France;Service de Pneumologie, Hôpital Gabriel Montpied, CHU Clermont-Ferrand, Clermont-Ferrand, France;EFFI-STAT, Paris, France;Service de Pneumologie, Hôpital de la Croix-Rousse, Lyon, France;Service de Pneumologie, Hôpital Calmette, Lille, France

关键词: Age;    Lung function;    Clinical expression;    Gender;    COPD;   

Others  :  790471
DOI  :  10.1186/1465-9921-15-20

 received in 2013-12-23, accepted in 2014-02-14,  发布年份 2014

【 摘 要 】

Reports regarding gender-related differences in COPD expression have provided conflicting results. In the French Initiatives BPCO real-world cohort, which contained 688 patients (146 women) when data were extracted, women were matched with men (1:3 ratio: n = 107:275) on age (5-year intervals) and FEV₁ (5% predicted intervals) and comparisons were performed using univariate logistic regressions. For a given age and level of airflow obstruction, women with COPD had higher BOD scores due to more pronounced dyspnea and lower BMI, suggesting worse prognosis, and were more likely to exhibit anxiety, suggesting the need for specific assessment and care.

【 授权许可】

   
2014 Roche et al.; licensee BioMed Central Ltd.

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