Improving medication adherence in chronic obstructive pulmonary disease: a systematic review

Respiratory Research

Jessica Melville²  Christine Paul²  Rob Sanson-Fisher²  Allison Boyes²  Vanessa M McDonald¹  Jamie Bryant² 

[1] School of Nursing and Midwifery, University of Newcastle, Callaghan, NSW 2308, Australia;Priority Research Centre for Health Behaviour, University of Newcastle & Hunter Medical Research Institute, HMRI Building, University of Newcastle, Callaghan, NSW 2308, Australia

关键词: Systematic review;    Chronic obstructive pulmonary disease;    Medication compliance;    Medication adherence;   

Others  :  792512
DOI  :  10.1186/1465-9921-14-109

 received in 2013-06-11, accepted in 2013-10-14,  发布年份 2013

【 摘 要 】

Adherence to medication among individuals with chronic obstructive pulmonary disease (COPD) is suboptimal and has negative impacts on survival and health care costs. No systematic review has examined the effectiveness of interventions designed to improve medication adherence. Electronic databases Medline and Cochrane were searched using a combination of MeSH and keywords. Eligible studies were interventions with a primary or secondary aim to improve medication adherence among individuals with COPD published in English. Included studies were assessed for methodological quality using the Effective Practice and Organisation of Care (EPOC) criteria. Of the 1,186 papers identified, seven studies met inclusion criteria. Methodological quality of the studies was variable. Five studies identified effective interventions. Strategies included: brief counselling; monitoring and feedback about inhaler use through electronic medication delivery devices; and multi-component interventions consisting of self-management and care co-ordination delivered by pharmacists and primary care teams. Further research is needed to establish the most effective and cost effective interventions. Special attention should be given to increasing patient sample size and using a common measure of adherence to overcome methodological limitations. Interventions that involve caregivers and target the healthcare provider as well as the patient should be further explored.

【 授权许可】

   
2013 Bryant et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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