Nasal High-flow versus non-invasive ventilation in stable hypercapnic COPD: a preliminary report

Multidisciplinary Respiratory Medicine

Hubert Wirtz¹  Hans-Jürgen Seyfarth¹  Jens Bräunlich¹ 

[1] Department of Respiratory Medicine, University of Leipzig, Liebigstr. 20, Leipzig, 04103, Germany

关键词: High-flow nasal cannula;    Significant decrease in capillary pCO2;    Nasal High-flow;    Noninvasive ventilation;    Hypercapnia;    COPD;   

Others  :  1224344
DOI  :  10.1186/s40248-015-0019-y

 received in 2015-04-28, accepted in 2015-07-01,  发布年份 2015

【 摘 要 】

Background

There are no data available about effectiveness of Nasal High-flow (NHF)in chronic respiratory insufficiency.

Methods

Eleven COPD patients with stable hypercapnia were adjusted to NHF-system with a flow of 20 l/min. After six weeks patients were switched to non-invasive ventilation (NIV) for another six weeks period.

Results

NHF led to significant decreases in resting pCO ₂ . Between the devices we found no differences in pCO ₂levels.

Conclusions

NHF may thus be an alternative treatment device in stable hypercapnic COPD patients.

【 授权许可】

   
2015 Bräunlich et al.

【 图 表 】

Fig. 1.

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