Pediatric Asthma Mortality and Hospitalization Trends Across Asia Pacific Relationship With Asthma Drug Utilization Patterns

World Allergy Organization Journal

Bee Wah Lee¹  Stefan Ma²  Shu E Soh¹  Kun Lin Chua¹ 

[1] Department of Pediatrics, National University of Singapore, Singapore;Epidemiology & Disease Control Division, Ministry of Health, Singapore

关键词: short-acting β-agonists;    inhaled corticosteroids;    relievers;    controllers;    asthma drug utilization pattern;    asthma hospitalization trends;    asthma mortality trends;    pediatric asthma;    Asia Pacific;   

Others  :  1180881
DOI  :  10.1097/WOX.0b013e3181a7c288

【 授权许可】

   
2009 World Allergy Organization; licensee BioMed Central Ltd.

【 参考文献 】

• [1]Masoli M, Fabian D, Holt S, Beasley R, Global Initiative for Asthma (GINA) Program: The global burden of asthma: executive summary of the GINA Dissemination Committee report. Allergy 2004, 59(5):469-478.
• [2]Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, et al.: Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet 2006, 368(9537):733-743.
• [3]Pearce N, Aït-Khaled N, Beasley R, Mallol J, Keil U, et al.: Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2007, 62(9):758-766.
• [4]Lim DL, Ma S, Wang XS, Cutter J, Chew SK, et al.: Trends in sales of inhaled corticosteroids and asthma outcomes in Singapore. Thorax 2006, 61(4):362-363.
• [5]Suissa S, Ernst P: Use of anti-inflammatory therapy and asthma mortality in Japan. Eur Respir J 2003, 21(1):101-104.
• [6]Gupta R, Anderson HR, Strachan DP, Maier W, Watson L: International trends in admissions and drug sales for asthma. Int J Tuberc Lung Dis 2006, 10(2):138-145.
• [7]Kumana CR, Kou M, Lauder IJ, Ip MS, Lam WK: Increasing use of inhaled steroids associated with declining asthma mortality. J Asthma 2001, 38(2):161-167.
• [8]Sly RM: Decreases in asthma mortality in the United States. Ann Allergy Asthma Immunol 2000, 85(2):121-127.
• [9]Bollag U, Capkun G, Caesar J, Low N: Trends in primary care consultations for asthma in Switzerland, 1989-2002. Int J Epidemiol 2005, 34(5):1012-1018.
• [10]Adams RJ, Fuhlbrigge A, Finkelstein JA, Lozano P, Livingston JM, Weiss KB, Weiss ST: Impact of inhaled antiinflammatory therapy on hospitalization and emergency department visits for children with asthma. Pediatrics 2001, 107(4):706-711.
• [11]Suissa S, Ernst P: Inhaled corticosteroids: impact on asthma morbidity and mortality. J Allergy Clin Immunol 2001, 107(6):937-944.
• [12]Nelson HS: Is there a problem with inhaled long-acting beta-adrenergic agonists? J Allergy Clin Immunol 2006, 117(1):3-16.
• [13]Sears MR: Adverse effects of beta-agonists. J Allergy Clin Immunol 2002, 110(6 suppl):S322-S328.
• [14]Suissa S, Ernst P, Boivin JF, Horwitz RI, Habbick B, et al.: A cohort analysis of excess mortality in asthma and the use of inhaled beta-agonists. Am J Respir Crit Care Med 1994, 149(3):604-610.
• [15]Lai CK, De Guia TS, Kim YY, Kuo SH, Mukhopadhyay A, et al.: Asthma control in the Asia-Pacific region: the Asthma Insights and Reality in Asia-Pacific Study. J Allergy Clin Immunol 2003, 111(2):263-268.
• [16]WHO Statistical Information Service [Mortality database] Available at: http://www.who.int/whosis/mort/download/en/index.html webcite. Accessed July 10 2008
• [17]Australian Centre for Asthma Monitoring: Asthma in Australia 2005. Canberra: Australian Institute of Health and Welfare; 2005. Asthma Series 2
• [18]Yeh KW, Fang W, Huang JL: Increasing the hospitalization of asthma in children not in adults - from a national survey in Taiwan 1996-2002. Pediatr Allergy Immunol 2008, 19(1):13-19.
• [19]Anderson HR, Gupta R, Kapetanakis V, Asher MI, Clayton T, et al.: International correlations between indicators of prevalence, hospital admissions and mortality for asthma in children. Int J Epidemiol 2008, 37(3):573-582.
• [20]Frischer M, Heatlie H, Chapman S, Norwood J, Bashford J, Millson D: Should the corticosteroid to bronchodilator ratio be promoted as a quality prescribing marker? Public Health 1999, 113(5):247-250.
• [21]Shelley M, Croft P, Chapman S, Pantin C: Is the quality of asthma prescribing, as measured by the general practice ratio of corticosteroid to bronchodilator, associated with asthma morbidity? J Clin Epidemiol 2000, 53(12):1217-1221.
• [22]GINA: Global Strategy for Asthma Management and Prevention [report]. December 2008. Available at: http://www.ginasthma.org webcite. Accessed February 3, 2009
• [23]SPSS for Windows [computer program]. Version 16.0.1 Chicago: SPSS Inc.; 2008.
• [24]ISAAC Steering Committee: Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC). Eur Respir J 1998, 12(2):315-335.
• [25]Beasley R, Crane J, Lai CKW, Pearce N: Prevalence and etiology of asthma. J Allergy Clin Immunol 2000, 105(2):S466-S472.
• [26]National Asthma Council Australia [Web site]Available at: http://www.nationalasthma.org.au/html/home/index.asp webcite. Accessed October 10, 2008
• [27]Asthma Foundations Australia [Web site]Available at: http://www.asthmaaustralia.org.au webcite. Accessed October 10, 2008
• [28]Chong PN, Tan NC, Lim TK: Impact of the Singapore National Asthma Program (SNAP) on preventor-reliever prescription ratio in polyclinics. Ann Acad Med Singapore 2008, 37(2):114-117.
• [29]Stafford RS, Ma J, Finkelstein SN, Haver K, Cockburn I: National trends in asthma visits and asthma pharmacotherapy, 1978-2002. J Allergy Clin Immunol 2003, 111(4):729-735.
• [30]Lau JT, Yang X, Tsui HY, Kim JH: Impacts of SARS on health-seeking behaviors in general population in Hong Kong. Prev Med 2005, 41(2):454-462.