Oral contraceptives and antibiotics. A cross-sectional study about patients’ knowledge in general practice

Reproductive Health

Manfred Maier²  Anna Katharina Leifheit²  Lukas Heschl²  Aaron George¹  Kathryn Hoffmann² 

[1] Department of Community and Family Medicine, Duke Medical Center, 2301 Erwin Rd, Box 3886, Durham 27705, USA, North Carolina;Department of General Practice and Family Medicine, Centre for Public Health, Medical, University of Vienna, Kinderspitalgasse 15/I 1st floor, Vienna, 1090, Austria

关键词: Austria;    Family planning;    Primary care;    Health literacy;    Knowledge;    Oral contraceptive pill;    Antibiotic interaction;   

Others  :  1210980
DOI  :  10.1186/s12978-015-0037-4

 received in 2014-10-24, accepted in 2015-05-06,  发布年份 2015

【 摘 要 】

Background

The evidence regarding oral contraceptives and its effectiveness with concomitant ingestion of antibiotics is conflicting. Until evidence becomes clearer, patients should be aware of this possible interaction. The aim of this study was to assess the knowledge and the source of information about this interaction in GP patients in Austria.

Methods

Within the framework of the APRES study, 20 Austrian GPs were purposefully selected from among a GP research network and were asked to recruit 200 patients each. The patient cohort was asked to complete a questionnaire. Subsequent analysis included descriptive statistics, statistical tests and logistic regression models.

Findings

Overall, 3280 questionnaires could be used for analysis. Of these, 29.7 % (n = 974) of patients acknowledged an awareness of the interaction of antibiotics with OCPs. Women under the age of 46 years acknowledged this interaction in 52.3 % of cases. Positive associations for the belief in an existing interaction in women were identified with age (OR 2.2) and having read the package inserts (OR 1.6). Further, belief was recognized in males based on age (OR 2.5) and tertiary education (OR 2.0). The main source of information regarding antibiotics was the GP (55.9 %).

Conclusions

Less than one-third of all participants and half of the women in the reproductive age acknowledged an interaction between antibiotics and OCPs. Since the GP is the main source of information, this finding depicts a large potential for knowledge transfer within the primary health care setting. A multifaceted strategy is needed at both the population and the GP level to improve awareness and to address these educational gaps.

【 授权许可】

   
2015 Hoffmann et al.; licensee BioMed Central.

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