Cystic tumor of the liver without ovarian-like stroma or bile duct communication: two case reports and a review of the literature

World Journal of Surgical Oncology

Yuko Kitagawa⁴  Michiie Sakamaoto²  Minoru Tanabe³  Akihiro Tanimoto¹  Hiroshi Yagi⁴  Yuta Abe⁴  Taizo Hibi⁴  Minoru Kitago⁴  Akihisa Ueno¹  Yoko Fujii-Nishimura²  Osamu Itano⁴  Yohei Masugi²  Masahiro Shinoda⁴  Norihiro Kishida⁴ 

[1]Department of Diagnostic Radiology, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan

[2]Department of Pathology, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan

[3]Department of Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan

[4]Department of Surgery, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan

关键词: Intraductal papillary neoplasm of bile duct;    Mucinous cystic neoplasm;    Bile duct communication;    Ovarian-like stroma;    Liver;    Cystic neoplasm;   

Others  :  1148582
DOI  :  10.1186/1477-7819-12-229

 received in 2013-11-17, accepted in 2014-07-04,  发布年份 2014

【 摘 要 】

We report two cases of cystic neoplasm of the liver with mucinous epithelium in which both ovarian-like stroma and bile duct communication were absent. The first case was a 41-year-old woman. She underwent right trisegmentectomy due to a multilocular cystic lesion, 15 cm in diameter, with papillary nodular components in the medial segment and right lobe. Histologically, arborizing papillae were seen in the papillary lesion. The constituent neoplastic cells had sufficient cytoarchitectural atypia to be classified as high-grade dysplasia. The second case was a 60-year-old woman. She underwent left lobectomy due to a unilocular cystic lesion, 17 cm in diameter, in the left lobe. Histologically, the cyst wall was lined by low columnar epithelia with slight cellular atypia. In both cases, neither ovarian-like stroma nor bile duct communications were found throughout the resected specimen. According to the most recent World Health Organization (WHO) classification in 2010, cystic tumors of the liver with mucinous epithelium are classified as mucinous cystic neoplasms when ovarian-like stromata are found, and as intraductal papillary neoplasm of bile duct when bile duct communication exists. Therefore, we diagnosed the cystic tumors as ‘biliary cystadenoma’ according to the past WHO classification scheme from 2000. We believe that the combined absence of both ovarian-like stroma and bile duct communication is possible in mucinous cystic tumors of the liver. Herein, we have described the clinicopathologic features of the two cases and reviewed past cases in the literature.

【 授权许可】

   
2014 Kishida et al.; licensee BioMed Central Ltd.

【 图 表 】

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